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【单选题】
打架斗殴，违反社会治安管理规定，受到公安机关行政拘留处罚的，起步处分档次即为行政（）处分，最高可给予行政（）处分。A.
警告，降级
B.
记过，开除
C.
记大过，撤职
D.
降级，开除
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举一反三
【单选题】Cross-licensing agreements are increasingly common in the _____ industry.
A.
Transportation
B.
High-technology
C.
Construction
D.
Consumer durables
【单选题】Which of the following is not true about CRISPR/Cas9 system ?
A.
The system contains a gRNA and an exo nuclease
B.
CRISPR refers to c lustered regularly interspaced short palindromic repeat
C.
A gRNA guides the endonuclease to load on a DNA target and cut it
D.
It is a part of immunity system of bacterium used to resist the foreign DNA
E.
The system contains a gRNA and an endonuclease
【多选题】Which of the following statements about gene editing by CRISPR/Cas9 are correct?
A.
On Jan 21, 2018, The Wall Street Journal reported that 86 people in China have had their genes edited using CRISPR/Cas9.
B.
In April 2015, Chinese scientists reported results of an attempt to alter the DNA of non-viable human embryos using CRISPR/Cas9 to correct a mutation that causes β-thalassemia. The study had previously been rejected by both Nature and Science in part because of ethical concerns. The experiments resulted in changing only some genes, and had off-target effects on other genes. The researchers stated that CRISPR/Cas9 is not ready for clinical application in reproductive medicine.
C.
In April 2016, Chinese scientists were reported to have made a second unsuccessful attempt to alter the DNA of non-viable human embryos using CRISPR/Cas9 - this time to alter the CCR5 gene to make the embryo HIV resistant.
D.
Heritable modifications could have unintended and far-reaching consequences for human evolution, genetically (e.g. gene/environment interactions) and culturally (e.g. Social Darwinism). Altering of gametocytes and embryos to generate inheritable changes in humans was defined to be irresponsible.
【简答题】肺实变最早出现的体征是（ ）
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