Which of the following descriptions about diffuse nontoxic goiter are CORRECT?
A.
All diffuse nontoxic goiter is not endemic
B.
Most patients of diffuse nontoxic goiter are with hypothyroidism
C.
Lymphocytic infiltration in interfollicular stroma is common in diffuse nontoxic goiter
D.
A compensatory rise in the serum TSH is the direct cause of hypertrophy and hyperplasia of thyroid follicular cells
E.
Diffuse nontoxic goiter is an auto-immune disease