【单选题】A 43-year-old woman has become increasingly tired and listless over the past 5 months. She has had menometrorrhagia for the past 3 months. On physical examination, there are no remarkable findings exc...
A.
Mutation in a DNA mismatch-repair gene
B.
Germline inheritance of APC gene mutation
C.
Tyrosine kinase activation owing to c-KIT mutation
D.
Homozygous loss of PTEN gene
E.
Inactivation of the Rb protein by HPV-16