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【多选题】
关于妊娠期胆汁成分的描述正确的是：A.
妊娠期胆汁成分无变化
B.
妊娠期胆汁的成分发生明显变化
C.
妊娠中期和晚期胆汁中胆固醇的成分明显增加
D.
妊娠中期和晚期胆汁中胆固醇的成分明显减少
E.
妊娠中期和晚期胆汁中胆固醇的成分无变化
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