【R1】 A. EXPERIMENTAL THERAPY. B. NEW AIDS DRUGS. C. AIDS LONGEVITY. D. AIDS TREN D. E. FEDERAL POLICY. MEDICAL SCIENTISTS CONTINUED TO INVESTIGATE WAYS TO BRING AIDS UNDER CONTROL IN 1989 AND 1990. THE DEVELOPMENT OF NEW DRUGS AND THE PROGRESS TOWARD CREATING AN AIDS VACCINE GENERATED HOPE AMONG THOSE INFECTED WITH THE DISEAS E. NEVERTHELESS, AIDS CONTINUED TO TAKE AN ENORMOUS TOLL ON HUMAN LIF E. 【R1】______ AS OF JULY 31,1990, THERE WERE 143,286 REPORTED DEATH ACCORDING TO THE CENTERS FOR DISEASE CONTROL(CDC)IN ATLANTA, GA, MORE THAN 87,600 PEOPLE HAD DIED OF AIDS. THE NUMBER OF NEW AIDS CASES GREW BY ABOUT 9 PERCENT IN 1989. THIS WAS THE SMALLEST ANNUAL INCREASE SINCE THE CDC BEGAN TRACKING THE DISEASE IN 1981. THE US PUBLIC HEALTH SERVICE IN JUNE 1990 ESTIMATED THAT THE NUMBER OF DIAGNOSED AIDS CASES WILL CLIMB TO BETWEEN 390,000 AND 480,000 BY 1994. ABOUT 1 MILLION PEOPLE IN THE UNITED STATES ARE INFECTED WITH HIV, WHICH CAUSE AIDS, THE NUMBER OF AIDS CASES AROUND THE WORLD ALSO CONTINUED TO GROW. IN JUNE 1990, THE WORLD HEALTH ORGANIZATION PROJECTED THAT AS MANY AS 20 MILLION PEOPLE WORLDWIDE WILL BE INFECTED WITH THE AIDS VIRUS BY THE YEAR 2000. 【R2】______ THE FDA ON JA N. 29, 1990, APPROVED A DRUG CALLED FLUCONAZOLE FOR THE TREATMENT OF AIDS-RELATED CONDITIONS. THE DRUG CAN TREAT TWO SERIOUS FUNGAL INFECTIONS COMMON IN AIDS PATIENTS. A PROMISING EXPERIMENTAL DRUG DDI RAN INTO PROBLEMS IN 1990. IN MARCH, RESEARCHERS AT THE NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES ANNOUNCED THAT SIX AIDS PATIENTS TAKING THE DRUG HAD DIED OF SEVERE INFLAMMATION OF THE PANCREAS. THIS SERIOUS SIDE EFFECT WAS CORROBORATED BY TWO STUDIES PUBLISHED IN MAY. THE RESEARCHERS NOTED, HOWEVER, THAT MOST OF THE SIDE EFFECTS OCCURRED AT DOSES MUCH HIGHER THAN THOSE NOW GIVEN TO PATIENTS. PRELIMINARY REPORTS ALSO SHOWED THAT DDI COULD HALT THE REPLICATION OF THE AIDS VIRUS AND THAT IT MIGHT BE A USEFUL ALTERNATIVE TREATMENT FOR PATIENTS WHO COULD NOT TOLERATE THE SIDE EFFECTS OF AZT. 【R3】______ RESEARCHERS AT THE JOHNS HOPKINS SCHOOL OF MEDICINE IN BALTIMORE REPORTED IN 1989 THAT THEY MAY HAVE RID A PATIENT OF THE AIDS VIRUS. THE RESEARCHERS COMBINED AZT TREATMENT WITH BONE MARROW(髓)TRANSPLANTATION IN A MAN WHO HAD BOTH AIDS AND LYMPHOMA, A TYPE OF CANCER THAT OCCURS IN THE LYMPH(淋巴腺)NODES. IN THE TRANSPLANT PROCEDURE, PHYSICIANS DESTROYED THE MAN'S BONE MARROW WITH RADIATION AND CHEMOTHERAPY AND THEN GAVE HIM HEALTHY BONE MARROW FROM A DONOR. THE MAN, WHO LATER DIED OF CANCER, WAS APPARENTLY FREE OF THE AIDS VIRUS WHEN TESTED 32 DAYS AFTER THE TRANSPLANT. ALTHOUGH THIS FIRST REPORT OF A WAY TO ELIMINATE HIV FROM A PATIENT'S BODY SEEMS-PROMISING, EXPERTS CAUTIONED THAT WIDE USE OF THE TECHNIQUE MAY BE IMPRACTICAL, AND THAT MORE TESTING IS NEEDE D. 【R4】______ THE SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH REPORTED IN JANUARY 1990 THAT PEOPLE WITH AIDS ARE LIVING LONGER TODAY, DUE TO IMPROVED DIAGNOSIS AND TREATMENT WITH AZT. PATIENTS TAKING THE ANTIVIRAL DRUG HAD A MEDIAN LIFE EXPECTANCY OF ABOUT 21 MONTHS AFTER DIAGNOSIS, COMPARED WITH 14 MONTHS AMONG THOSE NOT TAKING THE DRU G. SOME AIDS PATIENTS IN THE SAN FRANCISCO STUDY HAD SURVIVED EIGHT YEARS AFTER THEIR DIAGNOSIS. IN JUNE 1990, A NATIONAL CANCER INSTITUTE REPORT SHOWED A SHARP INCREASE IN THE INCIDENCE OF LYMPHOMA AMONG AIDS PATIENTS, PRESUMABLY BECAUSE THEIR WEAKENED IMMUNE SYSTEM MAKES THEM MORE SUSCEPTIBLE TO THIS KIND OF CANCER. SCIENTISTS PLANNED TO STUDY WHETHER AZT SOMEHOW CONTRIBUTES TO THE OCCURRENCE OF LYMPHOMA. 【R5】______ IN A REPORT TO US PRESIDENT GEORGE BUSH IN APRIL 1990, THE NATIONAL COMMISSION ON AIDS, A FEDERAL ADVISORY GROUP, COMPARED THE GOVERNMENT'S AIDS EFFORT TO 'AN ORCHESTRA WITHOUT A CONDUCTOR. ' THE COMMISSION CLAIMED THAT THE FEDERAL GOVERNMENT HAD NOT LED AN EFFECTIVE CAMPAIGN AGAINST THE DISEASE, AND IT URGED THE BUSH ADMINISTRATION TO ESTABLISH A NATIONAL PLAN TO ATTACK THE AIDS EPIDEMI C. ONE MONTH LATER, ON MARCH 29, PRESIDENT BUSH MADE HIS FIRST MAJOR SPEECH CONCERNING AIDS SINCE HE TOOK OFFIC E. HE ASKED AMERICANS TO SHOW COMPASSION TOWARD INDIVIDUALS WHO ARE INFECTED WITH HIV AND SAID THAT GOVERNMENT HEALTH AGENCIES WERE ON A 'WARTIME FOOTING' AGAINST THE DISEAS E. BUSH ALSO URGED CONGRESSIONAL APPROVAL OF A BILL THAT WOULD BAN DISCRIMINATION AGAINST AIDS PATIENTS. RYAN WHITE, WHO GAINED NATIONAL ATTENTION FOR FIGHTING BOTH AIDS AND THE PREJUDICE SURROUNDING THE DISEASE, DIED OF AIDS ON APRIL 8, 1990, AT AGE 18. WHITE CAME TO PROMINENCE IN 1985, WHEN HE SUCCESSFULLY FOUGHT A LEGAL BATTLE AGAINST SCHOOL OFFICIALS NEAR KOKOMO, IN D. FOR THE RIGHT TO ATTEND CLASS DESPITE HIS HIV INFECTIO N. WHITE EVENTUALLY BECAME AN ARTICULATE ADVOCATE FOR CHILDREN WITH AIDS. IN A STATEMENT PRESENTED AFTER WHITE'S DEATH, PRESIDENT BUSH SAID, 'RYAN'S DEATH REAFFIRMS THAT WE AS A PEOPLE MUST PLEDGE TO CONTINUE THE FIGHT, HIS FIGHT, AGAINST THIS DREADED DISEAS E. '