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【单选题】
下列慢性肾衰竭时用药应掌握的原则哪项不恰当
A.
了解常用药物的药代动力学和药效学特点；患者的肾功能情况及其他病理生理状况
B.
熟悉肾衰竭及其他病理生理状况时用药方法，按肾功能减退的程度调整某些药物特别是以原形经肾排泄的药物剂量
C.
首先选用肾毒性相对较小的药物，如确需应用某些有肾毒性的药物，应根据相应的方法减少药物剂量，或延长用药间隔
D.
对某些特殊治疗药物，如有条件可测定其血中药物浓度，如地、氨茶碱、苯妥英钠、氨基糖苷类抗菌药物等
E.
已经开始维持性血液透析治疗的慢性肾衰竭患者不需要调整用药剂量
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