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【单选题】
患者，男，43岁，患冠心病，近期心绞痛频发，医生给予硝酸甘油，并特别嘱其要舌下含服，而不采用口服，这是因为A.
可使毒性反应降低
B.
防止产生耐受性
C.
可使副作用减小
D.
避开首关消除
E.
防止耐药性产生
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