A50-year-old man has had increasing abdominal discomfort and swelling of his legs for the past 2 years. He has smoked cigarettes for 35 years. On physical examination, he has jugular venous distention, even when sitting up. The liver is enlarged and tender and can be palpated 10 cm below the right costal margin. Pitting edema is observed on the lower extremities. A chest radiograph shows bilateral diaphragma ic flattening, pleural effusions, and increased lucency of lung fields. Thoracentesis on the right side yields 500 mL of clear fluid with few cells. Which of the following is most likely to be the underlying disease in this patient?