Hepatitis (肝炎) means 'inflammation (发火) of the liver', and its most common cause is infected with one of 5 viruses, called hepatitis 【S1】______ A, B, C, D, and E. All of these viruses can cause an acute disease with symptoms lasting several weeks including yellowing of the skin and eyes, dark urine, extreme fatigue, vomiting and abdominal pain. It can take several months for a year to feel fit again. 【S2】______ Hepatitis C (HCV) is the most prevalent liver disease in the world. The World Health Organization consider Hepatitis C an epidemic. 【S3】______ Because Hepatitis C can infect a patient for decades after being 【S4】______ discovered, it is often called the 'silent' epidemic. According to the Center for Disease Control (CDC), 20-30% of people with chronic Hepatitis C will eventually face life-threatened symptoms. 【S5】______ Currently, it is estimated there are about 270 to 300 million people worldwide who are infected with HCV, 4 million of who are in the 【S6】______ United States. The prevalence seems to be high in Eastern Europe than 【S7】______ in Western Europe. In industrialized countries, HCV accounts of 20% 【S8】______ of cases of acute hepatitis, 70% of cases of chronic hepatitis, 40% of cases of end-stage cirrhosis (硬化), 60% of cases of liver cancer and 30-40% of liver transplants. The incidence of new symptomatic infections of HCV have been estimated to be 13 cases out of 100,000 【S9】______ people annually. For every one person that is infected with the AIDS virus, there are more than four infected with HCV. The CDC (Center for Disease Control) estimates that there arc up to 26,000 new HCV infections in the U.S. every year, and for that Hepatitis C causes 10,000 【S10】______ to 12,000 deaths each year. 【S1】