【简答题】完形填空 Once there was a very brilliant, creative and educated man. He gained much _ _1_ _ while traveling throughout the world. Unfortunately he lost his legs and left arm in a tragic accident, leaving ...
It is a major site in which t he γ-tubulin s combine with several other associated proteins to act as a scaffold for α - β tubulin dimers during the nucleation process .
B.
It is a cytoskeletal component composed of a family of related proteins sharing common structural and sequence features , which are cytoplasmic and nuclear localization .
C.
It is composed of a double-helical polymer of the protein actin, and play s a key role in virtually all types of contractility and motility within cells.
D.
It comprise s a superfamily of ATP -dependent motor proteins which are responsible for actin -based motility.
E.
It is composed of three distinct types of fibrous structures: microtubules, intermediate filaments, and microfilaments, which participate in a number of cellular activities.
F.
It is a protein belonging to a class of motor proteins found in eukaryotic cells . Most of them walk towards the positive /minus end of a microtubule .
G.
It is a family of cytoskeletal motor proteins that move toward the microtubules' plus end .
【多选题】Which of the following statements about Wernicke-Korsakoff syndrome are correct?
A.
Wernicke-Korsakoff syndrome is a disorder caused by a severe deficiency of thiamine (vitamin B 1 ), a component of TPP. The syndrome is more common among people with alcoholism than in the general population, because chronic, heavy alcohol consumption interferes with the intestinal absorption of thiamine.
B.
The syndrome can be exacerbated by a mutation in the gene for transketolase that results in an enzyme with a lowered affinity for TPP—an affinity one-tenth that of the normal enzyme.
C.
This defect makes individuals much more sensitive to a thiamine deficiency: even a moderate thiamine deficiency (tolerable in individuals with an unmutated transketolase) can drop the level of TPP below that needed to saturate the enzyme. The result is a slowing down of the whole pentose phosphate pathway.
D.
In people with Wernicke-Korsakoff syndrome this results in a worsening of symptoms, which can include severe memory loss, mental confusion, and partial paralysis.
It is a major site in which t he γ-tubulin s combine with several other associated proteins to act as a scaffold for α - β tubulin dimers during the nucleation process .
B.
It is a cytoskeletal component composed of a family of related proteins sharing common structural and sequence features , which are cytoplasmic and nuclear localization .
C.
It is composed of a double-helical polymer of the protein actin, and play s a key role in virtually all types of contractility and motility within cells.
D.
It comprise s a superfamily of ATP -dependent motor proteins which are responsible for actin -based motility.
E.
It is composed of three distinct types of fibrous structures: microtubules, intermediate filaments, and microfilaments, which participate in a number of cellular activities.
F.
It is a protein belonging to a class of motor proteins found in eukaryotic cells . Most of them walk towards the positive /minus end of a microtubule .
G.
It is a family of cytoskeletal motor proteins that move toward the microtubules' plus end .