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【单选题】
D-环丝氨酸在细菌肽聚糖合成过程中有抑制作用,其抑菌机理是( )。
A.
与PEP结构类似,竞争抑制PEP-UDP-N-乙酰葡萄糖胺转移酶活性。
B.
与肽聚糖单体五肽尾末端D-丙氨酰-D-丙氨酸的结构类似物,竞争抑制转肽酶活性。
C.
与D-丙氨酸-D-丙氨酸结构类似,抑制丙氨酸消旋酶和D-丙氨酸-D-丙氨酸合成酶。
D.
与细菌萜醇结合,抑制载体的再生。
E.
与N-乙酰胞壁酸五肽焦磷酸-十一异戊烯中五肽上的D-丙氨酸-D-丙氨酸末端结合,阻止肽聚糖亚单位移动到肽聚糖生长点。
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