Which of the following statements regarding nitroglycerine is incorrect?
A.
Nitroglycerine can cause adverse reactions of headache and tachycardia.
B.
Nitroglycerine undergoes significant first-pass biotransformation.
C.
Nitroglycerine is used for congestive heart failure intravenously.
D.
Nitroglycerine increases total coronary blood flow.
E.
If continuous intravenous infusions of nitroglycerine are used for more than a few hours without interruption, tolerance may develop.