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【单选题】
关于消化性溃疡的癌变，下列哪项是正确的
A.
各种消化性溃疡均有癌变可能
B.
癌变发生于溃疡边缘
C.
癌变率可达10%以上
D.
症状经严格的4内科治疗无改善
E.
癌变率与年龄无关
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