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【多选题】
对父母进行染色体检查的适应症是
A.
生过智力低下、多发畸形患儿
B.
有自然流产和不育史
C.
高龄孕妇
D.
生过先天性代谢病患儿
E.
生过常染色体显性或隐性遗传病的患儿
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A.
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exclude
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