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根据以下材料,回答题 Cancer Drug Trials Often Halted Early An increasing number of clinical trials for new cancer treatments are being halted before the risks and benefits have been fully evaluated, say Italian researchers, who warn that this growing trend could put patients at risk of harm from new therapies rushed into use. The researchers looked at 25 randomized, controlled clinical trials that were stopped early because the treatments had started to show benefit to patients. 'When we analyzed 25 trials over a 10-year period between 1997 and 2007, we found a consistent increase in prematurely stopped trials——more than 50 percent were stopped within the last three years,' study co-author Giovanni Apolone said at a news conference Tuesday. Of 14 trials halted early and published between 2005 and 2007, the researchers found that 11(79 percent) of them were used to support drug approval applications submitted to the European Medicines Agency and the U.S. Food and Drug Administration. 'This suggests a strong commercial component in stopping trials prematurely. In fact, this strategy could guarantee quicker access to the market for companies. On the other hand, a quicker clinical drug development may lead to an 'immature' benefit/risk balance of new drugs,'Apolone said. He and his colleagues 'are aware that trials stopped early because they are showing benefit may result in identification of promising new treatments for patients. However, findings obtained following this strategy should be considered to be preliminary results that require subsequent confmnation.' It can take several years for the long-term benefits or harmful side effects of a new treatment to become apparent, Apolone noted, but the average duration (持续时间) of the 25 studies he and his colleagues analyzed was 30 months, with a range from 12 to 64 months. They also found that at the time five of the studies were stopped, they'd enrolled less than 40 percent of the total number of patients planned for final analysis. 'Clinical trials need to stop early for superior benefit whenever there's proof beyond reasonable doubt that the new treatment really is superior. That would be an ethical obligation,'Stuart Pocock, a professor of medical statistics at the London School of Hygiene and Tropical Medicine in the United Kingdom, said at the news conference. 'However, too many trials are stopped early claiming efficacy (功效) without strong evidence being available.' The number of prematurely stopped clinical trials has increased recently. 查看材料
A.
Right
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Wrong
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Not mentioned
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【简答题】已知 298.15K 时下列反应的热效应数值如下: 4C 2 H 5 Cl(g) + 13O 2 (g) → 2Cl 2 (g) + 8CO 2 (g) + 10H 2 O(g) △ r H m =-5144.6 kJ·mol -1 ; 计算反应 在 298.15K 时的△ r U m 。
【简答题】计算下列反应的(1) (298.15K);(2) (298.15K);(3)298.15K进行1mol反应时的体积功w。
【单选题】一个部落或种族在历史的发展中灭绝了,但它的文字会留传下来。“亚里洛”就是这样一种文字。考古学家是在内陆发现这种文字的。经研究“亚里洛”中没有表示“海”的文字,但有表示“冬”、“雪”、“狼”的文字。因此,专家们推测,使用“亚里洛”文字的部落或种族在历史上生活在远离海洋的寒冷地带。以下哪项如果为真,最能削弱专家上述推测?
A.
蒙古语中有表示“海”的文字,尽管古代蒙古人从没见过海
B.
“亚里洛”中有表示“鱼”的文字
C.
“亚里洛”中有表示“热”的文字
D.
“亚里洛”中没有表示“山”的文字
【判断题】企业拥有的经济资源,只要预期给企业带来经济利益就可以确认为资产。
A.
正确
B.
错误
【单选题】一个部落或种族在历史的发展中灭绝了,但它的文字会留传下来。“亚里洛”就是这样一种文字。考古学家是在内陆发现这种文字的。经研究,“亚里洛”中没有表示“海”的文字,但有表示“冬天”、“雪”和“狼”等的文字。因此,专家们推测,使用“亚里洛”文字的部落或种族在历史上生活在远离海洋的寒冷地带。 以下哪项如果为真,最能削弱上述专家的推测?
A.
蒙古语中有表示“海”的文字,尽管古代蒙古人从没见过海。
B.
“亚里洛”中有表示“鱼”的文字。
C.
“亚里洛”中有表示“热”的文字。
D.
“亚里洛”中没有表示“云”的文字。
【判断题】变压器的副边电流向原边进行折算时,需要保持折算前后的磁势关系不变。
A.
正确
B.
错误
【简答题】已知298.15K时,下列反应的 : =-143.7kJ·mol -1 =-11.5kJ·mol -1 求298.15 K时CuO的标准生成焓 。
【简答题】对于下列反应: 平衡时,c B 3+ 及C A 2+ 分别为2.00×10 -2 mol·L -1 和5.00×10 -3 mol·L -1 ,计算298.15K时上述反应的 及 。
【简答题】计算下列反应的(1)△rHΘm(298.15 K);(2)△rHΘm(298.15 K);(3)298.15 K进行1mol反应时的体积功W。 CH4(g)+4Cl2(g)=CCl4(l)+4HCl(g)
【简答题】求298.15K时下列反应 的 。已知各物质在298.15K时的热力学数据如下:
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