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【单选题】
男性，48岁，双手近端指间、腕关节肿痛6个月，伴晨僵>2h／d，ESR80mm（第1小时末），CRP升高，RF1：48，ANA阴性。双手X线片示：骨质疏松，腕关节轻度狭窄关于类风湿性关节炎，下列说法不正确的是（）
A.
发病和免疫反应有关
B.
RA最基本病理变化是滑膜炎
C.
血中类风湿因子本质是IgM抗体
D.
类风湿因子具有诊断价值
E.
RF提示预后较差
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举一反三
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【单选题】watch the videoclip and make a choice 2 The instructions and the test are the same as they were in 1932(A) / easier than those in 1932(B)
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