The rapid, pervasive, and truly unprecedented transformation resulting from science and technology is a central fact of our lives. It calls for the strengthening of institutional capability for objective, scholarly analysis of critical issues based on a broad foundation of knowledge and experience. Colleges and universities, academies, and freestanding institutes can mobilize a wide range of talent to address the great issue of our time in a sustained, fascinating, and effective way. They can give us a better chance to get the complex facts straight and to clarify the most promising options--all this in a way that is in--credible and even intelligible to nonspecialists. Such efforts can be helpful to open-minded policy-makers, but also-and perhaps more importantly in the long run--to the education of a broadly informed public on the great issues of our time and the policy choices available to us. Surely the problems associated with the social and economic concomitants of technological change are not insuperable. The opportunities provided by the advancing technology, if wisely utilized, suggest that it is worth a lot of trouble and hard work to find ways to make a decent social adjustment. What is the best alternative of the word 'address' in the first paragraph?