A runner ’ s muscles use glucose as a source of energy. Muscle contains glycogen stores that are degraded into glucose 1-phosphate via glycogen phosphorylase, which is an allosteric enzyme. Assume that an allosteric enzyme has the following kinetic properties: a Vmax of 25 U/mg enzyme and a Km,app of 1.0 mM. These kinetic parameters were then measured in the presence of an allosteric activator. Which one of the following would best describe the findings of that experiment?
A.
A Vmax of 25 U/mg enzyme and a Km,app of 0.2 mM
B.
A Vmax of 15 U/mg enzyme with a Km,app of 2.0 mM
C.
A Vmax of 25 U/mg enzyme with a Km,app of 2.0 mM
D.
A Vmax of 50 U/mg enzyme with a Km,app of 5.0 mM
E.
A Vmax of 50 U/mg enzyme with a Km,app of 10.0 mM