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【单选题】
变态反应是指A.
药物引起的反应与个体体质有关，与用药剂量无关
B.
剂量过大或药物在体内蓄积过多时发生危害性反应
C.
突然停药后原有疾病复发或加重
D.
长期用药，需逐渐增加剂量，保持药效不减
E.
长期用药，产生生理上的依赖，停药后出现戒断症状
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