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【多选题】
根据Noyes-Whitney方程原理，制备缓、控释制剂可采用的方法有A.
控制药物的粒子大小
B.
将药物制成溶解度小的盐或酯
C.
将药物包藏于不溶性骨架中
D.
包衣
E.
增加制剂的黏度
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