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【单选题】
女孩，4岁。因外院诊断为先天性心脏病而来检查：胸骨左缘可闻及响亮而粗糙的全收缩期杂音，肺动脉第二音稍增强。心动图检查诊断为室间隔缺损，由于该畸形首先可以引起以下哪一方面的改变（）
A.
左心室增大
B.
右心室增大
C.
左心房扩大
D.
主动脉扩张
E.
肺动脉扩张
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