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【多选题】
What is Niemann-Pick type-C (NPC) disease?A.
Niemann-Pick type-C (NPC) disease is an inherited defect in lipid storage. In this disorder, cholesterol is not transported out of the lysosomes and instead accumulates in lysosomes of liver, brain, and lung, bringing about early death.
B.
NPC is the result of a mutation in either of two genes, NPC1 and NPC2 , essential to moving cholesterol out of the lysosome and into the cytosol, where it can be further metabolized.
C.
NPC1 encodes a transmembrane lysosomal protein, and NPC2 encodes a soluble protein.
D.
These proteins act in tandem to transfer cholesterol out of the lysosome and into the cytosol for further processing or metabolism.
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举一反三
【单选题】设函数f(x)在点x0处连续，则下列结论肯定正确的是（ ）．
A.
B.
C.
当x→x0时, f(x)- f(x0)不是无穷小量
D.
当x→x0时, f(x)- f(X0)必为无穷小量
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A.
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【单选题】某初孕妇,32岁。妊娠38周,腹部触诊,宫底可触及圆而硬的胎儿部分,腹部右侧凹凸不平,左侧相对平坦,胎心音脐上左侧听得最清楚。该孕妇胎儿胎位可能是
A.
枕右前位
B.
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C.
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E.
肩右前位
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